Within the scope of the study, a total of 160 cats, 96 males and 64 females, who fell from height between August 2016 and August 2017, were retrospectively evaluated. In addition to the age, gender, breed, neutering status, clinical and radiographic findings of the cats, the answers given to the questions asked to the cat owners about the changes in the house they lived in, pre-existing diseases, and the presence of medication they were constantly using were evaluated to obtain new data on the etiology. The average age of the cats was 15.8 months. 65.6% of the cats were 12 months and younger. It was observed that 109 (68%) of the cats fell from height between April and July, and July was the month with the highest number of falls from height with 40 patients. Injury scores increased in direct proportion to the height of the fall. There was a linear correlation between falls from height and increased daytime hours. The survival rate of the cats was 93.4%. In conclusion, future studies on high-rise syndrome in cats should focus more on the effect of sex hormones, and that screening for parasitic and some bacterial agents such as Toxoplasma gondii, which is known to increase suicidal tendency in humans, may yield important results. In addition, it was seen that evaluating the ratio of unspayed female cats in countries with temperate climates where doors and windows can be left open for a long period of the year could make an important contribution to the etiology of this syndrome.