Eubiotics, which include prebiotics, probiotics, synbiotics, postbiotics, and organic acids, have been used in poultry and livestock production for a long time. These eubiotics play a pivotal role in sustainable livestock and poultry production by improving gut health, enhancing immune responses, and improving overall animal performance. These eubiotics are effective against a wide range of bacteria, fungi, toxins, and other pathogens. In these eubiotics, there are adequate substitutes for antibiotic-resistant bacteria (AAD), thereby reducing the risk of treatment failure due to the transfer of resistance genes. Among eubiotics, probiotics hold the most tremendous significance. Probiotics encompass non-pathogenic strains of various organisms. The beneficial activities of probiotics include improving gut microbial balance (gut homeostasis), as well as immune-modulatory and anti-inflammatory effects against gut inflammation or chronic low-grade inflammation. Additionally, they resist pathogens in the gut, thereby enhancing animal performance through improved feed conversion ratio (FCR), increased body weight gain, and reduced mortality. Similarly, other eubiotics serve to strengthen gut health and ultimately lead to ornamental animal performance. Thus, objectives of this review are to look into the detailed description of eubiotics, composition, and benefits, which render these a superior alternative to antibiotics in animal feed. Moreover, it is hoped that this article will be of interest to both scientists and field veterinarians as it aims to improve the gut health of animals, thereby enhancing productivity and overall performance.

To Cite This Article: Du X, Maqbool B, Shichiyakh R, Haque MA, Aubakirov M, Syamsu JA and Khan A, 2025. Eubiotics improve gut health and overall production in animals by reducing pathogenic bacteria. Pak Vet J, 45(2): 488-498. http://dx.doi.org/10.29261/pakvetj/2025.186