Aflatoxicosis and Ochratoxicosis in Broiler
Chicks and their Amelioration with Locally Available Bentonite Clay
Sheraz Ahmed Bhatti*,
Muhammad Zargham Khan, Muhammad Kashif Saleemi and Muhammad Saqib1
Department of Pathology; 1Department
of Clinical Medicine and Surgery, University of Agriculture,
Faisalabad *Corresponding author:dr_sheraz03@yahoo.com
Abstract
The present study was designed to investigate the
ameliorative ability of locally available bentonite clay (BN) against aflatoxin
B1 (AFB1) and ochratoxin A (OTA) toxicity in broiler chicks. In the first
experiment the broiler chicks were
kept on feeds contaminated with AFB1 (0.1, 0.2 and 0.6 mg/kg) alone and in
combination with bentonite clay (3.7
and 7.5 g/kg). In the second experiment OTA (0.15, 0.3 and
1.0 mg/kg) alone and concurrently with bentonite clay (3.7, 7.5 and 15 g/kg) was fed to the broiler chicks. The dietary addition
of AFB1 and OTA alone exerted deleterious effects on the performance, sero-biochemical
and oxidative status of the broiler chicks. A concurrent dietary incorporation of BN (3.7 and 7.5 g/kg)
ameliorated the adverse effects of 0.1 and 0.2 mg/kg AFB1 on body weight, FCR,
serum ALT and urea concentration. Serum creatinine, total protein and albumin
concentrations were mostly significantly lower in combination groups suggesting
a partial or no amelioration. Dietary incorporation of BN at all levels only
partially alleviated the deleterious effects of 0.15 and 0.3 mg/kg dietary OTA
on performance, serobiochemical and oxidative stress, but amelioration was
absent when the concentration of OTA in the feed was 1 mg/kg. Results suggested
that the dietary incorporation of BN (3.7 and 7.5 g/kg) ameliorated the adverse
effects of 0.1 and 0.2 mg/kg of AFB1 on various parameters. However, BN at all
levels did not alleviate the deleterious effects of OTA.
Key words:
Aflatoxin B1,
Bentonite Clay,Broiler birds, Ochratoxin A