previous page   Pak Vet J, 2017, 37(2): 236-238   next page
The Dedifferentiate Tumor of the Bursa of Fabricius and the Intestinal Mucosa Associated Lymphoid Tissue in Quail (Coturnix coturnix): Case Report
C Solcan, M Spataru, C Spataru, V Floristean* and G Solcan
University of Agricultural Science and Veterinary Medicine Ion Ionescu de la Brad, Faculty of Veterinary Medicine, M. Sadoveanu Alley 8, Iasi, 700489, Romania
*Corresponding author:


After examination of 150 female quails, four of them showed the dedifferentiate tumor of the bursa of Fabricius. To the periphery, it consists of the dedifferentiate hemangiosarcoma and liposarcoma, the predominant area being constituted from lymph nodes of variable sizes. Among the lymphocytes rows the extensions of the reticular cells appeared positive for MHC II antibody. The lymphocytes showed the negativity to p53. The Bcl-2 marker manifested a limited positive reaction only in certain follicles. IgA and IgM markers showed the relatively low level of positivity in lymph nodes. Only the dense cords of the pleomorphic melanocytes manifested the positivity to Bcl-2. At the junctions between ventriculus and duodenum; ileum and cecum, especially in serosa, there were identified lymphocytes positive to MHC II, Bcl-2 and p53 markers surrounded by clusters of lipoid cells located inside the intestine wall. These structures were metastases of the dedifferentiate tumor of the bursa of Fabricius.

Key words: Bursa of Fabricius, Dedifferentiate tumor, Hemangiosarcoma, Immunohistochemistry, Liposarcoma, Quail


ISSN 0253-8318 (Print)
ISSN 2074-7764 (Online)