Feasibility of 99mTc-Phytate as a Lower
Lymphoscintigraphic Agent in Dogs
Youngkwon Cho1 and Kichang Lee2*
1Veterinary Clinical
Service, College of Veterinary Medicine,Chonbuk
National University Specialized Campus : 79 Gobong-ro, Iksan-si,
Jeollabuk-do 54596 Republic of Korea; 2Department of Veterinary Medicine, Chonbuk National University, Iksan
570-752, Korea;
*Corresponding author:kclee@jbnu.ac.kr
Abstract
The purpose of this study was to evaluate
availabilities of nuclear medicine images that could replace lower
lymphangiography using conventional radio-pharmaceutical. Six beagles were
performed lymphoscintigraphy after injected with 300 microcurie of 99mTc-phytate
in 0.2ml, widely used in human medicine subcutaneously on
1st and 2nd interdigital space each of hind legs. To get images of popliteal
lymph node, inguinal lymph node, iliac lymph node and thoracic duct, animals
were laid supine beneath a gamma camera, and images at 0, 30, 60 and 120 min
were obtained. The uptake rate of popliteal lymph node, bladder, and liver was
measured in acquisitioned image. In this study, the image of popliteal lymph
node is simply like that of a human, but it was not available for other lymph
nodes above popliteal lymph node. Voluntary exercise or
massage was not performed in anesthesia condition and that could be the reason
for limitation in upper moving of radiopharmaceuticals. In conclusion, 99mTc-phytate has a limitation for
lower lymphoscintigraphy in dogs.