Oxidative stress due to assembly of excessive reactive oxygen species (ROS) is responsible for damage of biomolecules that may lead to cell death. Search of symbiotic bacteria with antioxidant properties is an active area of research for medical and veterinary practitioners. Present study is conducted to compare antioxidant and probiotic potential of four strains of Lactobacillus brevis (MG882399, MG882400, MG882401 and MG882402) with one reference strain of antioxidant property possessing bacteria, L. acidophilus ATCC 4356, and two commercial probiotic bacteria, Bifidobacterium longum BB536 and L. rhamnosus GG ATCC 53103. The antioxidant potential of intact cells, cell free supernatant (CFS) and cell lysate of all strains was investigated for scavenging of α-diphenyl-β-picrylhydrazyl, Superoxide dismutase, Hydroxyl radical and inhibition of lipid peroxidation. Cell lysate was noticed to possess least antioxidant activity while intact cells and CFS were found to show similar antioxidant potential. Among our strains L. brevis MG882402 was found superior in all tests and displayed better probiotic and antioxidant competence as compared to B. longum, L. rhamnosus, and L. acidophilus. It was selected for further evaluation through in vivo procedures.

To Cite This Article: Noureen S, Riaz A, Saif A, Arshad M, Qamar MF and Arshad N, 2018. Antioxidant properties of Lactobacillus brevis of horse origin and commercial lactic acid bacterial strains: a comparison. Pak Vet J, 38(3): 306-310. http://dx.doi.org/10.29261/pakvetj/2018.067